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Meniere's Disease


Described by French ear specialist, Prosper Meniere, in 1861, Meniere's Disease is characterized by three symptoms:



Many patients, however, do not develop the three typical symptoms of Meniere's Disease at once, but may first suffer from attacks of either hearing loss or vertigo. These patients usually go on to develop the classic combination of symptoms months or years later.


There are rarer variations of the disease, including one during which hearing actually improves. Another variation is characterized by drop attacks, during which patients suffer such sudden, intense vertigo that they fall to the ground. The severity, frequency, and length of Meniere's Disease attacks are extremely variable. Some people experience several episodes a day while others have them only once every several years.

Meniere's Disease Progression

The other variable in Meniere's Disease is its progression. Research has revealed that about two thirds of all patients go into a spontaneous remission. This means the disease disappears for an extended period of months or years with or without treatment. The disease may the flare up for several weeks or months and disappear again.


For most patients, though, the hearing in the affected ear gradually deteriorates over a period of months to years and is eventually lost. More than 15 to 20 percent of patients develop the condition in both ears. However, it is unusual for these patients to develop active Meniere's in both ears at the same time.


In fact, Meniere's Disease charts a slow, intermittent course in most patients. It bothers them for weeks or months and then disappears for extended periods. Only a minority of patients have severe vertigo or rapid hearing loss.


The inner ear is a complex series of chambers within the base of the skull. These chambers are filled with fluid and are further subdivided by thin membranes. Although the exact cause of Meniere's Disease is uncertain, researchers believe that it results from an imbalance in fluid pressures between the different chambers.


The composition of the fluid In the chambers is quite different, and if one of the membranes bursts from unequal pressure, fluid from the different compartments will mix. This causes a breakdown of the hearing and balance systems, and Meniere's symptoms result.


Once the fluid drains and pressure is restored, the leak in the membrane heals. Normal fluid composition is restored and the balance and hearing functions gradually return to normal.


Do You Have Meniere's Disease?

There are several conditions which cause Meniere's like symptoms but have known causes and can be successfully treated. These conditions, called Meniere's Syndrome, range from untreated syphilis to head injury. In many cases, when the underlying conditions are treated, the Meniere's symptoms disappear.


There are literally hundreds of causes of dizziness. It is not a condition. but a symptom, and anyone who develops dizziness, should have his or her balance system, hearing and blood tested to rule out any treatable conditions.


Treatments for Meniere's Disease

Medical Treatment
There have been a variety of medical measures proposed for treating Meniere's Disease such as salt restricted diets and diuretics. Research has revealed, however, that there is no benefit from those treatments for any great length of time. There are medications available which can temporarily relieve the dizziness associated with Meniere's Disease. One commonly prescribed drug, meclizine, is similar to Dramamine, a common over-the-counter drug taken for motion sickness. Neither drug has a true effect on the balance center of the brain, and does not stop the spinning. However, it sedates, the patient and suppresses nausea. A drawback to this treatment is that the pills take about 40 minutes to work, and by that time most Meniere's attacks have subsided. Some patients can sense an attack is coming, however, and can sometimes benefit from taking the medication in advance.


Surgical Treatment
There are a variety of surgical treatments which have been proposed for Meniere's Disease, but no treatment has ever been shown to preserve hearing. Treatment is therefore directed toward control of vertigo, which can be dangerous. There are four common operations for Meniere's Disease. Each is directed toward the relief of dizziness, but will not arrest progress of the disease or hearing loss in the affected ear. Each operation has different levels of benefit and risk. You and your physician will decide if surgical treatment is best for you, and if so, which operation would help most.


The first operation is called a labyrinthotomy or cochleo-sacculotomy. This is a brief surgical procedure done using local anesthesia. During the operation, an opening is made between two of the fluid chambers of the inner ear to allow the pressure to equalize. About half the patients who have this operation suffer some loss of high tone hearing in the affected ear. From the first year after the operation, however, 90% of them will be free of vertigo. Three years after surgery, 70% are still free of vertigo. This is a very effective procedure for patients with severe vertigo, who still have useful hearing in the affected ear.


The second operation is called a sac decompression. During this two to three hour procedure, pressure is relieved in the sac where the fluid of the inner ear drains into the spinal fluid space. This helps inner ear fluid drain more easily, and prevents the high pressure which researchers believe causes Meniere's. About two thirds of the patients who have this surgery seem to get better and the complication rate is extremely low.


The third operation, called a vestibular nerve section, has a high success rate but is the most complex. During the procedure, the surgeon will cut the vestibular nerve, which carries the balance signal from the inner ear to the brain. The success rate for eliminating dizzy spells using this procedure is about 95%. Because the balance nerve is cut, patients are usually quite dizzy for a period of days or weeks following surgery. Gradually, the balance system on the other side of the head, compensates and the dizziness disappears.


The fourth operation to control dizziness from Meniere's Disease has a 98% success rate, but guarantees a total loss of hearing in the affected ear. The procedure is called a labyrinthectomy and is only for patients who have little or no hearing left in the affected ear. During the procedure all of the membranes of the inner ear are removed. Like patients who have undergone vestibular nerve sections, labyrinthectomy patients are usually dizzy for a period of days or weeks until the other side compensates. The dizziness, however, is usually not as severe in labyrinthectomy patients.


In summary, Meniere's Disease is a disorder of the inner ear which produces episodes of vertigo and progressive nerve deafness. A thorough examination by a qualified ear, nose and throat specialist is needed to make the diagnosis and exclude other treatable or dangerous causes of these symptoms. symptoms of Meniere's disease tend to alternately flare up and then subside over the years. Those infrequent cases with incapacitating vertigo can be relieved with a variety of surgical procedures.


Additional Information

We hope that this brochure has been helpful. If you have specific questions which are not answered here, please feel free to call the Infirmary's General Ear, Nose, and Throat Service at (617) 573-4101. Or, if you would like to schedule an appointment for an examination by an Infirmary otolaryngologist, a physician who specializes in the medical and surgical treatment of the ear , nose, and throat, please call our Physician Referral Service at (617) 523-6334.


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See also our online fact sheet on meniere's




page updated: 9/16/05